专利名称：ENHANCEMENT OF THE ACTION OF
CENTRAL AND PERIPHERAL NERVOUSSYSTEM AGENTS
发明人：MEYER, Petrus, Johannes申请号：EP01959903.4申请日：20010719公开号：EP1476195A2公开日：20041117
摘要：The invention provided a method of enhancing the action of a pharmaceuticalagent selected from the group consisting of the CPNS agents selected from the groupof compounds acting on the central or peripheral nervous system, and for a formulationof such agents characterised in that the agent is formulated with an administrationmedium which is characterised in that it comprises a solution of nitrous oxide gas in apharmaceutically acceptable carrier solvent for the gas and which administration mediumincludes at least one fatty acid or ester or other suitable derivative thereof selected fromthe group consisting of oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid,arachidonic acid, eicosapentaenoic acid [C20: 5φ3], decosahexaenoic acid [C22: 6φ3],ricinoleic acid and derivatives thereof selected from the group consisting of the C1 to C6alkyl esters thereof, the glycerol-polyethylene glycol esters thereof and the reactionproduct of hydrogenated natural oils composed largely of ricinoleic acid based oils suchas castor oil with ethylene oxide.
申请人：PITMY INTERNATIONAL N.V.
地址：Kaya Gob,Nicolaas Debrot 33 Bonaire AN
国籍：AN
代理机构：Bates, Philip Ian
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