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Inhibitors of syk and JAK protein kinases

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专利名称:Inhibitors of syk and JAK protein kinases发明人:Zhaozhong Jia,Chandrasekar

Venkataramani,Wolin Huang,MukundMehrota,Yonghong Song,Qing Xu,Shawn M.Bauer,Jack W. Rose,Brian Kane,Anjali Pandey

申请号:US12386525申请日:20090416

公开号:US20100048567A1公开日:20100225

摘要:The present invention is directed to compounds of formula I-V and tautomersthereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which areinhibitors of syk kinase. The present invention is also directed to intermediates used inmaking such compounds, the preparation of such a compound, pharmaceuticalcompositions containing such a compound, methods of inhibition syk kinase activity,methods of inhibition the platelet aggregation, and methods to prevent or treat anumber of conditions mediated at least in part by syk kinase activity, such as undesiredthrombosis and Non Hodgkin's Lymphoma.

申请人:Zhaozhong Jia,Chandrasekar Venkataramani,Wolin Huang,Mukund

Mehrota,Yonghong Song,Qing Xu,Shawn M. Bauer,Jack W. Rose,Brian Kane,Anjali Pandey

地址:San Mateo CA US,Redwood City CA US,Foster City CA US,South San Francisco CAUS,Foster City CA US,Foster City CA US,Pacifica CA US,San Mateo CA US,Pleasant Hill CAUS,Fremont CA US

国籍:US,US,US,US,US,US,US,US,US,US

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