专利名称:GLUCOSYLCERAMIDE SYNTHASE
INHIBITORS
发明人:Elyse BOURQUE,Mario A. CABRERA-SALAZAR,Cassandra CELATKA,Seng H.CHENG,Bradford Hirth,AndrewGOOD,Katherine JANCSICS,JohnMARSHALL,Markus Metz,Ronald K.
SCHEULE,Renato SKERLJ,Yibin XIANG,ZhongZHAO,John LEONARD,Thomas NATOLI,ElinaMAKINO,Herve HUSSON,OxanaBESKROVNAYA
申请号:US190385申请日:20170418
公开号:US20180065957A1公开日:20180308
专利附图:
摘要:The invention relates to inhibitors of glucosylceramide synthase (GCS) useful forthe treatment of metabolic diseases, such as lysosomal storage diseases, either alone orin combination with enzyme replacement therapy, cystic disease and for the treatment ofcancer.
申请人:Genzyme Corporation
地址:Cambrdige MA US
国籍:US
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