专利名称：RECOMBINANT RNA PARTICLES AND
METHODS OF PRODUCING PROTEINS
发明人：Robert C. Brown,Kurt I. Kamrud申请号：US15236144申请日：20160812
公开号：US20170044555A1公开日：20170216
摘要：The present invention provides compositions and methods for the productionand delivery of recombinant double-stranded RNA molecules (dsRNA) encodingheterologous proteins, which can be useful for various therapeutic purposes as well asfor the production of desired proteins. The compositions contain engineered double-stranded RNA particles (dsRPs) that can contain a double-stranded RNA molecule thatcan be a genome or portion of a genome, which can be enclosed in a capsid or coatprotein. The dsRNA molecule also comprises an RNA sub-sequence that encodes aheterologous protein. The dsRPs can be derived from wild-type viral organisms. Thedelivery of the dsRPs (or DNA or RNA molecules) of the invention to an organismprovides for therapeutic benefits as well as for the production of desired proteins.
申请人：Synthetic Genomics, Inc.
地址：La Jolla CA US
国籍：US
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