sample-paper

Department of Health and Human Sciences

BSc Undergraduate Awards Scheme Examination

Cell Biology BM1002N [SAMPLE PAPER]

Module Convenor: Dr C.Bax

Date:

Time: 1hour 30 minutes

THIS PAPER WILL BE COLLECTED AT THE END OF THE EXAMINATION

Maximum marks for this paper: 100

Answer ALL questions. Write your answers in the spaces provided on the question paper. NAME AND ID NUMBER:

1. Complete EACH of the following:

a) 2000 l = cm3

b) 0.5 ml = l

c) 10nm = Å

d) The molarity of a 0.87% isotonic NaCl saline solution =

(the relative molecular mass of NaCl = 58)

mmol dm-3

5 marks

2. 3.

What is understood by the term cell theory?

3 marks

Name THREE components of the extracellular matrix, indicating the role of EACH one.

6 marks

4.

Complete EACH of the following equations, indicating the potential ATP yield for :

a) the complete aerobic oxidation of carbohydrate (CH2O) 6 + 6O2 →

b) the anaerobic oxidation of carbohydrate to lactic acid (CH2O) 6 →

c) the anaerobic fermentation of carbohydrate to ethanol (CH2O) 6 →

9 marks

5.

a) Draw a labelled diagram of a prokaryotic cell as seen in a transmission electron micrograph; indicating the cell's dimensions.

b) State TWO ways in which the structure of a prokaryotic cell differs from that of a eukaryotic cell.

13 marks

6.

Comment on the role of EACH of the following plasma membrane constituents: a) phospholipids

b) Sterols (e.g. cholesterol)

6 marks

7. Indicate by means of a tick (√ ) or a cross (x) which cellular uptake mechanism is associated with EACH of the following properties: Property Simple Facilitated Acive diffusion diffusion transport Transport down a concentration gradient Transport against a concentration gradient Does not require cellular enregy Requires cellular energy Does not display a maximum rate at high concentrations Does display a maximum rate at high concentrations 18 marks

8. Name the organelles associated with EACH of the following: Cellular protein synthesis Protein synthesis for export Degradation reactions Electron transport chains Synthesis of lipids Utilisation of light energy 6 marks

9. Name the FOUR main families of receptors.

8 marks

10. Fill in the gaps to complete the following passage:

The intracellular second messenger adensine triphosphate by the action of the enzyme .

is formed from ; this enzyme is activated by intracellular GTP-binding proteins called

6marks

11. Fill in the gaps to complete the following passage:

Prophase I of is a lengthy process and is usually subdivided into five stages. During the first stage, second stage, zygotene, and , the

chromosomes become visible as thin threads under the light microscope. During the

chromosomes pair up. Aligned . During the third stage, pachytene,

chromosomes are held together within the synaptonemal complex that is made up of

or physical exchange of genetic material takes place

between the paired chromosomes. During the fourth stage, diplotene, the

synaptonemal complex breaks down and the chromatids move apart as if repulsed. However, the sister chromatids of individual chromosomes remain joined at the and pairs of chromosomes are still held together by

.

18 marks

between non-sister chromatids. The final stage, diakinesis, is

the time of maximum chromosome

Which one of the following statements is correct: a) Interphase consists of G1, G2 and M

b) Interphase consists of G1, G2 and S

c) DNA synthesis occurs during G1 d) DNA synthesis occurs during G2 e) DNA synthesis occurs during M

END OF PAPER

2 marks

12.