INHIBITION OF Ii EXPRESSION IN MAMMALIAN CELLS

专利名称：INHIBITION OF Ii EXPRESSION IN

MAMMALIAN CELLS

发明人：XU, Minzhen,HUMPHREYS, Robert申请号：EP03721783.3申请日：20030418公开号：EP1575985A2公开日：20050921

摘要：The present invention is directed toward composition and methods involvingthe inhibition of Ii expression in cells for the purpose of altering antigen presentationpathways. More specifically, disclosed are compositions and methods which relate toMHC Class II molecule presentation of antigenic epitopes which, under normal

circumstances, would not be presented in association with MHC Class II molecules. Theinvention relates to presentation in cells which normally express MHC Class II molecules,as well as cells which can be induced to express MHC Class II molecules.

申请人：ANTIGEN EXPRESS, INC.

地址：10 Barber Avenue Worcester, MA 01606 US

国籍：US

代理机构：Modiano, Guido

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