专利名称:STROMAL DELLS DERIVED CONDITIONED
MEDIUM, METHOD OF OBTAINING SAIDCONDITIONED MEDIUM COMPOSITIONS,FORMULATIONS AND APPLICATIONSTHEREOF
发明人:Sudha BALASUBRAMANIAN,Swathi SUNDAR
RAJ,Charan THEJ,Ramesh RAMCHANDRABHONDE,Raviraja NEELAVARSEETHARAM,Anish SEN MAJUMDAR
申请号:US14912306申请日:20140618
公开号:US20160206550A1公开日:20160721
摘要:The present disclosure relates to a conditioned medium (CM) enriched withbioactive factor, its composition and the method of producing the CM. The method ofobtaining the desired quantity of bioactive factors in conditioned medium comprises ofpooling bone marrow derived mesenchymal stromal/stem cells, culturing the pooled celland subjecting the cell culture to a cell feeding schedule at specified confluency andcollecting the potent conditioned medium rich in bioactive factors at specificpassage/time period. The method further aims at maximizing the probability of
generating a conditioned medium with reduced biological variability and comprising largenumber of bioactive factors having specific biological function/property. The disclosurealso relates to composition and formulation of the conditioned medium and their use in
cosmetic and therapeutic areas.
申请人:STEMPEUTICS RESEARCH PVT. LTD.
地址:Karnataka, India,Bangalore IN
国籍:IN
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